Ethanolamine → HCID 54255644, compound

HRID 597376Notes

Reaction equation

HRID 597376 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:11][CH3:12])[CH:10]=1)[CH:6]=O.[NH:13]1[CH2:19][C:17](=[O:18])[NH:16][C:14]1=[O:15].C(CN)O>O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:11][CH3:12])[CH:10]=1)[CH:6]=[C:19]1[NH:13][C:14](=[O:15])[NH:16][C:17]1=[O:18]

Participants

5

Reactant 3

HCID 700EthanolamineHCID 10006HydantoinHCID 817473,5-Dimethoxybenzaldehyde

Product 1

HCID 54255644HCID 54255644, compoundYield 76.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 3,5-dimethoxybenzaldehyde (2.550 g.) and hydantoin (1.505 g., 1 molar ratio) in water (15 ml) was heated to 70°. Monoethanolamine (1.38 g., 1.5 molar ratio) was added and the 2 layer liquid mixture was magnetically stirred at 90°-92° (bath temperature) for 4 hours. Isolation in the usual manner gave the title compound as a beige solid (2.870 g.), m.p. 285°-287°.

Workup

  1. temperaturewas heated to 70°

Sources & evidence

ORD record
ord-94ed53cbdaaf4942bf542a335c011c61
Source dataset
uspto-grants-1977_03
Patent number
US04013770

Reaction notes

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