HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Bis(methylthio)-2-nitroethylene → 1-Nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Bis(methylthio)-2-nitroethylene | HCID 83623 | — |
| Reactant | HCID 178510959 | HCID 178510959 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-Nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene | HCID 178503821 | — |
Reaction Steps
A solution of 4-(4-aminobutyl)imidazole (from the dihydrobromide (3.6 g) and 1-nitro-2,2-bis-methylthioethylene (2.0 g)) in acetonitrile (50 ml) was set aside at room temperature for 3 days. The product was chromatographed on a column of silica gel with elution by ethyl acetate, to give 1-nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04013769 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-bd6e720c0e8f4ad785ec9cae8f4a554f |
| Source note | uspto-grants-1977_03 |