1,1-Bis(methylthio)-2-nitroethylene → HCID 178526914, compound

HRID 597402Notes

Reaction equation

HRID 597402 reaction equation
NCCSCCC1N=CNC=1.[N+](C=C(SC)SC)([O-])=O.[N+:21]([CH:24]=[C:25](SC)[NH:26][CH2:27][CH2:28][S:29][CH2:30][CH2:31][C:32]1[N:33]=[CH:34][NH:35][CH:36]=1)([O-:23])=[O:22].[NH2:39][CH2:40][CH2:41][S:42][CH2:43][C:44]1[C:49]([Cl:50])=[CH:48][CH:47]=[CH:46][N:45]=1>>[N+:21]([CH:24]=[C:25]([NH:39][CH2:40][CH2:41][S:42][CH2:43][C:44]1[C:49]([Cl:50])=[CH:48][CH:47]=[CH:46][N:45]=1)[NH:26][CH2:27][CH2:28][S:29][CH2:30][CH2:31][C:32]1[N:33]=[CH:34][NH:35][CH:36]=1)([O-:23])=[O:22]

Participants

5

Reactant 4

HCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 129515322-(3-Chloropyrid-2-ylmethylthio)ethylamineHCID 178503827HCID 178503827, compoundHCID 178511474HCID 178511474, compound

Product 1

HCID 178526914HCID 178526914, compound

Procedure

4-[2-(2-Aminoethylthio)ethyl]imidazole (from the dihydrobromide (4.0 g) is reacted with 1-nitro-2,2-bis-methylthioethylene (2.0 g) by the procedure of Example 8(i) and the resultant 1-nitro-2-methylthio-2-[2-(2-(4-imidazolyl)-ethylthio)ethylamino]ethylene is treated with 2-[(2-aminoethyl)thiomethyl]-3-chloropyridine by the procedure of Example 1 (a) (ii) to yield the title compound.

Sources & evidence

ORD record
ord-dcde3de2c5f747afa0e08979e14ce8f6
Source dataset
uspto-grants-1977_03
Patent number
US04013769

Reaction notes

Loading…