反应详情

By the procedure of Example 8(i), 2-(3-aminopropylthio)oxazole (2.1 g) is reacted with 1-nitro-2,2-bis-methylthioethylene (2.0 g) to give 1-nitro-2-methylthio-2-[3-(2-oxazolylthio)propylamino]ethylene (2.1 g) which, on reaction with 2-[(2-aminoethyl)thiomethyl]-3-chloropyridine by the procedure of Example 1 (a)(ii) gives the title product (2.2 g).