2-{[(3-Bromopyridin-2-yl)methyl]sulfanyl}ethan-1-amine → 1-Nitro-2-[2-((3-bromo-2-pyridyl)methylthio)ethylamino]-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene

HRID 597412Notes

Reaction equation

HRID 597412 reaction equation
[N+:1]([CH:4]=[C:5](SC)[NH:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)([O-:3])=[O:2].[NH2:18][CH2:19][CH2:20][S:21][CH2:22][C:23]1[C:28]([Br:29])=[CH:27][CH:26]=[CH:25][N:24]=1>>[N+:1]([CH:4]=[C:5]([NH:18][CH2:19][CH2:20][S:21][CH2:22][C:23]1[C:28]([Br:29])=[CH:27][CH:26]=[CH:25][N:24]=1)[NH:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 129515272-{[(3-Bromopyridin-2-yl)methyl]sulfanyl}ethan-1-amineHCID 705429481-(Methylsulfanyl)-2-nitro-N-(2-{[(1,3-thiazol-2-yl)methyl]sulfanyl}ethyl)ethen-1-amine

Product 1

HCID 706239691-Nitro-2-[2-((3-bromo-2-pyridyl)methylthio)ethylamino]-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene

Procedure

Reaction of 1-nitro-2-methylthio-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene with 2-[(2-aminoethyl)thiomethyl]-3 -bromopyridine according to the process of Example 1 (a)(ii) yields the title compound.

Sources & evidence

ORD record
ord-49cb717024b34c6dad8d54055017a5a1
Source dataset
uspto-grants-1977_03
Patent number
US04013769

Reaction notes

Loading…