2-(3-Chloropyrid-2-ylmethylthio)ethylamine → 1-Cyano-2-methoxy-2-[2-((3-chloro-2-pyridyl)methylthio)ethylamino]ethylene

HRID 597419Notes

Reaction equation

HRID 597419 reaction equation
[C:1]([CH:3]=[C:4](OC)[O:5][CH3:6])#[N:2].[NH2:9][CH2:10][CH2:11][S:12][CH2:13][C:14]1[C:19]([Cl:20])=[CH:18][CH:17]=[CH:16][N:15]=1>>[C:1]([CH:3]=[C:4]([O:5][CH3:6])[NH:9][CH2:10][CH2:11][S:12][CH2:13][C:14]1[C:19]([Cl:20])=[CH:18][CH:17]=[CH:16][N:15]=1)#[N:2]

Participants

3

Reactant 2

HCID 129515322-(3-Chloropyrid-2-ylmethylthio)ethylamineHCID 226227003,3-Dimethoxyprop-2-enenitrile

Product 1

HCID 705721731-Cyano-2-methoxy-2-[2-((3-chloro-2-pyridyl)methylthio)ethylamino]ethylene

Procedure

Reaction of 1-cyano-2,2-bis-methoxyethylene (J.A.C.S., 1949, 71, 47) with 2-[(2-aminoethyl)thiomethyl]-3-chloropyridine by the procedure of Example 1(b)(i) yields 1-cyano-2-methoxy-2-[2-((3-chloro-2-pyridyl)methylthio)ethylamino]-ethylene.

Sources & evidence

ORD record
ord-fc306e699a5e453b8b29be1142c38a95
Source dataset
uspto-grants-1977_03
Patent number
US04013769

Reaction notes

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