HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dehydroepiandrosterone → 11beta-Hydroxyestradiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dehydroepiandrosterone | HCID 5881 | — |
| Reactant | Progesterone | HCID 5994 | — |
| Reactant | Pregnenolone | HCID 8955 | — |
| Reactant | Androstenediol | HCID 10634 | — |
| Reactant | Dihydroandrostenedione | HCID 222865 | — |
| Reactant | 5alpha-Androstane-3beta,17beta-diol | HCID 242332 | — |
| Reactant | 19-Nor-5-androstenediol | HCID 9900246 | — |
| Reactant | 19-Nordehydroepiandrosterone | HCID 53990402 | — |
| Product | 11beta-Hydroxyestradiol | HCID 227673 | — |
Reaction Steps
This reduction procedure is useful for the preparation of the 11α-acid succinates of 11α-hydroxy analogs of dehydroepiandrosterone, pregnenolone, progesterone, 3β-hydroxy-estr-5-en-17-one, and 5α-androstane-3,17-dione to 11α-hydroxy succinate derivatives of androst-5-ene-3β,17β-diol, pregn-5-ene-3β,20α and 20β diols, pregn-4-ene-3,20α and 20β diols, estr-5-en-3β,17β-diol and 5α-androstane-3β,17β-diol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04013688 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-ce7257e7003f4e99b1e7535e164b02fd |
| Source note | uspto-grants-1977_03 |