HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-2-methyl-5-nitro-N-(pentan-3-yl)pyrimidin-4-amine → 2-Methyl-4-cyclopropoxy-5-nitro-6-(3-pentylamino)-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-2-methyl-5-nitro-N-(pentan-3-yl)pyrimidin-4-amine | HCID 15908584 | — |
| Reactant | Sodium cyclopropanolate | HCID 23699278 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Methyl-4-cyclopropoxy-5-nitro-6-(3-pentylamino)-pyrimidine | HCID 53773614 | — |
Reaction Steps
12.9 g of 2-methyl-4-chloro-5-nitro-6-(3-pentylamino)-pyrimidine (0.05 mole) are reacted in dimethyl sulphoxide (c. 100 ml) with 4.0 g of sodium cyclopropanolate (0.05 mole) to yield 2-methyl-4-cyclopropoxy-5-nitro-6-(3-pentylamino)-pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04014677 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-644acdd808a54e80a263c1a1a1944a4d |
| Source note | uspto-grants-1977_03 |