Isopropylamine → HCID 21445066, compound

HRID 597461Notes

Reaction equation

HRID 597461 reaction equation
[CH2:1]([C:3]1[N:8]=[C:7](Cl)[C:6]([N+:10]([O-:12])=[O:11])=[C:5]([Cl:13])[N:4]=1)[CH3:2].[CH:14]([NH2:17])([CH3:16])[CH3:15]>>[CH2:1]([C:3]1[N:4]=[C:5]([Cl:13])[C:6]([N+:10]([O-:12])=[O:11])=[C:7]([NH:17][CH:14]([CH3:16])[CH3:15])[N:8]=1)[CH3:2]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 2306474,6-dichloro-2-ethyl-5-nitropyrimidine

Product 1

HCID 21445066HCID 21445066, compoundYield 79.3%

Procedure

111 g (0.5 mole) of 2-ethyl-4,6-dichloro-5-nitro-pyrimidine are reacted with 59.1 g (1.0 mole) of isopropylamine. To yield 97 g of 2-ethyl-6-isopropylamino-5-nitro-4-chloro-pyrimidine of m.p. 51°-52° C.

Sources & evidence

ORD record
ord-27d2c347a3c443b6951ad96d99802987
Source dataset
uspto-grants-1977_03
Patent number
US04014677

Reaction notes

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