Acetic Anhydride → HCID 53785237, compound

Participants

Reaction Steps

(3S,6R,7R)-3-Hydroxy-7-phenylacetamidocepham (29 mg.) in dimethylsulphoxide (1 ml.) was treated with acetic anhydride (0.2 ml.) After being kept at 24° for 16 hour the reaction mixture was partitioned between brine and ethyl acetate. Removal of the ethyl acetate gave (6R,7R)-3-keto-7-phenylacetamidocepham (22 mg.). T.1.c. and g.1.c. data were in agreement with those obtained on material prepared in Example 3a. EXAMPLE 3d

Provenance & Evidence