HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 21445423, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 21445465 | HCID 21445465 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21445423 | HCID 21445423 | — |
Reaction Steps
Under the same conditions as described above, reaction of 17.7 g. of 5-chloro-N-(3-dimethylaminopropyl)-3-(2-fluorophenyl)-indole-2-carboxamide with 6.8 g. sodium hydride suspension in 250 ml. of dimethylformamide yielded after recrystallization from boiling dimethylformamide 13.5 g. (81 percent) of 10-chloro-5-(3-dimethylaminopropyl)-7H-indolo[2,3-c]quinolin-6(5H)-one, having a melting point of 286°-288°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04014883 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-3c4b73054a104e4ba2a082f56d0687ff |
| Source note | uspto-grants-1977_03 |