Aluminium lithium hydride → HCID 23346565, compound

HRID 597612Notes

Reaction equation

HRID 597612 reaction equation
[O:1]1[CH:12]2[C:2]1([CH3:15])[C:3]1([C:9]([CH3:14])([CH3:13])[CH2:10][CH2:11]2)[O:7][CH:6]([CH3:8])[CH:5]=[CH:4]1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:8][CH:6]1[CH:5]=[CH:4][C:3]2([C:9]([CH3:14])([CH3:13])[CH2:10][CH2:11][CH2:12][C:2]2([CH3:15])[OH:1])[O:7]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 23346563HCID 23346563, compound

Product 1

HCID 23346565HCID 23346565, compoundYield 90.5%

Procedure

2.08 g (0.01 M) of 6,7-epoxy-2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene -- see method B, letter i -- were reduced by means of 570 mg (0.015 M) of LiAlH4 in accordance with the above process. After the usual treatments of washing, drying and evaporation, the fractional distillation of the obtained residue gave 1.9 g (ca. 90 %) of 2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene-6-ol, b.p. 80°-90° /0.1 Torr.

Workup

  1. washAfter the usual treatments of washing
  2. customdrying
  3. customevaporation
  4. distillationthe fractional distillation of the obtained residue

Sources & evidence

ORD record
ord-97b93d175456476f98c0137ce63af80f
Source dataset
uspto-grants-1977_03
Patent number
US04014905

Reaction notes

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