Carbon Dioxide → HCID 53654074, compound

Participants

Reaction Steps

26.3 g (0.1 mol) of p-acetoxy-α-acetylaminocinnamic acid, 50 ml of quinoline and 2 g of copper powder are heated to 160°-170°C for 3 hours, in the course of which carbon dioxide is evolved. Thereafter, the quinoline is distilled off in vacuo and the residual mass is taken up in ethyl acetate. After filtering off the copper powder, the ethyl acetate solution is extracted with 25 ml of 1 N hydrochloric acid and is then washed with water and sodium bicarbonate solution. The organic phase is dried over sodium sulphate and thereafter the solvent is removed by distillation in vacuo. The resulting oil, on crystallisation from ethyl acetate, yields p-(2-acetylaminovinyl)-acetoxybenzene of melting point 165°-166°C.

Provenance & Evidence