HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 54169306, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-(3-Chloro-4-hydroxyphenyl)prop-2-enoic acid | HCID 53425719 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 54169306 | HCID 54169306 | — |
Reaction Steps
104 g (0.525 mol) of 3-chloro-4-hydroxy-cinnamic acid are dissolved in 530 ml of 2 N sodium hydroxide solution, 800 g of ice are added and 107 g (1.05 mols) of acetic anhydride are introduced dropwise over the course of 15 minutes at 0°-5° C, whilst stirring. The crystals which have precipitated are then filtered off, suction-dried and recrystallised from alcohol-water. 4-Acetoxy-3-chloro-cinnamic acid of melting point 210°-213° C is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04014920 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-5679ac667eed48c88f700d2480940575 |
| Source note | uspto-grants-1977_03 |