HCID 21446165, compound → HCID 21446148, compound

Participants

Reaction Steps

An amount of 128.7 g (0.69 mole) of 2-cyano-bicyclo[2.2.2]oct-5-ene-2-propionitrile is dissolved in 1.3 liters of the purest methanol; an addition is then made of 3 g of palladium charcoal (5% Pd) and hydrogenation performed at 15°-25° under normal pressure to effect a hydrogen absorption of 90% of theory. After removal by filtration of the catalyst, the solvent is evaporated off and the residue fractionated to obtain 2-cyano-bicyclo[2.2.2]octane-2-propionitrile, B.P. 114°-116°/0.01 Torr.

Provenance & Evidence