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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 597890Generated: October 31, 2026

Sodium Hydroxide → 5-(2,4-Dichlorophenyl)-4-methylpenta-2,4-dienoic acid

https://huagongshe.com/reaction/597890

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant5-(2,4-Dichlorophenyl)-4-methylpenta-2,4-dienoic acid ethyl esterHCID 72473003—
SolventEthanolHCID 702—
Product5-(2,4-Dichlorophenyl)-4-methylpenta-2,4-dienoic acidHCID 724731099.4%

Reaction Conditions

Temperature50 °C

Reaction Steps

5-(2,4-Dichlorophenyl)-4-methylpenta-2,4-dienoic acid ethyl ester (2.37 g, 0.083 mol) was suspended in EtOH (50 mL). 2 N NaOH (13 mL, 3 eq) was added and the mixture was heated at 50° C. for 1 hour. The mixture was cooled to room temperature and acidified to pH 1. The resulting solid was collected to give 2 g of 5-(2,4-dichlorophenyl)-4-methylpenta-2,4-dienoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897601B2
Source datasetuspto-grants-2011_03
ORD IDord-757727612bf84516a0b8008795a4c0f4
Source noteuspto-grants-2011_03