Aluminium lithium hydride → Ethyl 1-butyryl-6-mesityl-4-oxo-3,4-dihydro-2H-quinolizine-3-carboxylate

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Reaction Steps

Ethyl 1-butyryl-6-mesityl-4-oxo-4H-quinolizine-3-carboxylate (0.034 g, 0.084 mmol) was dissolved in tetrahydrofuran (1 mL). Lithium aluminum hydride (0.007 g, 0.17 mmol) was added at 0° C. After 15 minutes, the reaction was quenched with Glauber's salt. The solution was filtered, concentrated, and flash chromatographed (15% ethyl acetate/hexanes) to give the title compound (0.014 g, 41% yield).

Provenance & Evidence