反应详情

To 0.170 g (0.53 mmol) of 1-benzyl-5-chloro-3-chloromethylcinnolin-4(1H)-one in 6 mL of dimethylsulfoxide was added 0.050 g (1.3 mmol) of sodium borohydride. The reaction was stirred at room temperature for 3 h and diluted with water. The resulting precipitate was collected and dried to give 0.140 g (92%) of the title compound as a fluffy cream colored solid.

1. customThe resulting precipitate was collected
2. customdried