HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1S,2S)-2-aminocyclohexanol → 5-Bromo-N-((1S,2S)-2-hydroxy-cyclohexyl)-6-(2,2,2-trifluoro-ethoxy)-2-trifluoromethyl-nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (1S,2S)-2-aminocyclohexanol | HCID 7057408 | — |
| Edukt | 5-Bromo-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)nicotinic acid | HCID 86346320 | — |
| Produkt | 5-Bromo-N-((1S,2S)-2-hydroxy-cyclohexyl)-6-(2,2,2-trifluoro-ethoxy)-2-trifluoromethyl-nicotinamide | HCID 86634802 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1c, using 5-bromo-6-(2,2,2-trifluoro-ethoxy)-2-trifluoromethyl-nicotinic acid and (1S,2S)-2-amino-cyclohexanol as starting materials, MS (ISP) 465.1, 467.1 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07897621B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-c17efe6de2fb4124bc542f3848277c91 |
| Quellennotiz | uspto-grants-2011_03 |