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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 598423Generated: October 25, 2026

2-Bromo-1,3-thiazole-4-carboxylic acid → N-[2-(aminocarbonyl)-5-methylphenyl]-2-bromo-4-thiazolecarboxamide

https://huagongshe.com/reaction/598423

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1,3-thiazole-4-carboxylic acidHCID 2763209—
Reactant2-Amino-4-methylbenzamideHCID 2801474—
ProductN-[2-(aminocarbonyl)-5-methylphenyl]-2-bromo-4-thiazolecarboxamideHCID 57737845—

Reaction Steps

2-Bromo-4-thiazolecarboxylic acid and 2-amino-4-methylbenzamide are reacted in analogy to the synthesis of intermediate III.2 to give N-[2-(aminocarbonyl)-5-methylphenyl]-2-bromo-4-thiazolecarboxamide (intermediate III.3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897626B2
Source datasetuspto-grants-2011_03
ORD IDord-c8ab84fadb834aa2afb83789f490cd57
Source noteuspto-grants-2011_03