HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-7-(trifluoromethyl)quinoxaline → (5-Methyl-2-trifluoromethyl-phenyl)-[(R)-3-(7-trifluoromethyl-quinoxalin-2-ylamino)-pyrrolidin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-7-(trifluoromethyl)quinoxaline | HCID 21313161 | — |
| Reactant | ((R)-3-Amino-pyrrolidin-1-yl)-(5-methyl-2-trifluoromethyl-phenyl)-methanone | HCID 57748952 | — |
| Product | (5-Methyl-2-trifluoromethyl-phenyl)-[(R)-3-(7-trifluoromethyl-quinoxalin-2-ylamino)-pyrrolidin-1-yl]-methanone | HCID 57748916 | — |
Reaction Steps
In analogy to the procedure described for example 200, the title compound was prepared from 2-chloro-7-trifluoromethyl-quinoxaline and ((R)-3-amino-pyrrolidin-1-yl)-(5-methyl-2-trifluoromethyl-phenyl)-methanone (intermediate 13). (M+H+) 469.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897627B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-473659bad37644f5869384eed047af24 |
| Source note | uspto-grants-2011_03 |