化工社化工社 化学情報印刷レポート · 研究参考用
Benzofuran → (RS)-2-(1-Benzofuran-2-yl-methanoyl)-4-methyl-piperazine-1-carboxylic acid tert-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzofuran | HCID 9223 | — |
| 反応物 | (RS)-2-(methoxy-methyl-carbamoyl)4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester | HCID 86625772 | — |
| 生成物 | (RS)-2-(1-Benzofuran-2-yl-methanoyl)-4-methyl-piperazine-1-carboxylic acid tert-butyl ester | HCID 66968186 | 52% |
反応手順
The title compound (1.81 g, 52%) was prepared from (RS)-2-(methoxy-methyl-carbamoyl)-4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester, D54 (2.9 g, 10.1 mmol) and benzofuran (0.74 g, 10.1 mol) using the method of Description 2.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07897618B2 |
| 出典データセット | uspto-grants-2011_03 |
| ORD ID | ord-f6e7a548cb1f45b6ab5e8cefcf7a9380 |
| 出典メモ | uspto-grants-2011_03 |