HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylbenzofuran → (RS)-2-[1-(3-Methyl-benzofuran-2-yl)-methanoyl]-piperidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylbenzofuran | HCID 88939 | — |
| Reactant | tert-Butyl 2-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate | HCID 21988510 | — |
| Product | (RS)-2-[1-(3-Methyl-benzofuran-2-yl)-methanoyl]-piperidine-1-carboxylic acid tert-butyl ester | HCID 66968387 | — |
Reaction Steps
The title compound (300 mg) was prepared from 3-methyl-benzofuran (390 mg) and (RS)-1-(tert-butyloxycarbonyl)-2-(N-methoxy-N-methylcarbamoyl)-piperidine, D1 (820 mg) according to a procedure similar to that for Description 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897618B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-bff679aa167f46a697252ad4a68f3859 |
| Source note | uspto-grants-2011_03 |