Benzofuran → HCID 66968234, compound

HRID 598575Notes

Reaction equation

HRID 598575 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[CH:2]1.[C:10]([O:14][C:15]([N:17]1[CH2:21][CH2:20][CH2:19][CH:18]1[C:22](=[O:27])N(OC)C)=[O:16])([CH3:13])([CH3:12])[CH3:11]>>[C:10]([O:14][C:15]([N:17]1[CH2:21][CH2:20][CH2:19][CH:18]1[C:22]([C:2]1[O:1][C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=1)=[O:27])=[O:16])([CH3:13])([CH3:12])[CH3:11]

Participants

3

Reactant 2

HCID 9223BenzofuranHCID 3517120HCID 3517120, compound

Product 1

HCID 66968234HCID 66968234, compound

Procedure

The title compound (2.7 g) was prepared from benzofuran (2.29 g) and (RS)-2-(methoxy-methyl-carbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester, D79 (5.00 g) according to a procedure similar to that for Description 2.

Sources & evidence

ORD record
ord-37edf85762ce40e3bb77c83819aaef73
Source dataset
uspto-grants-2011_03
Patent number
US07897618B2

Reaction notes

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