HRID598608

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1nc(C(=O)N2CCN(C)CC2Cc2cc3cc(Cl)ccc3o2)c(-c2ccc(F)cc2)s1

HCID23146349

未命名化合物

结构：O=C1C(S(=O)(=O)[O-])=Cc2cc(S(=O)(=O)[O-])ccc2/C1=N/Nc1ccc(S(=O)(=O)[O-])c2ccccc12.[Na+].[Na+].[Na+]

HCID178516958

未命名化合物

PRODUCTS

生成物

结构：Cc1nc(C(=O)N2CCNCC2Cc2cc3cc(Cl)ccc3o2)c(-c2ccc(F)cc2)s1

HCID23146332

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 1-[2-(5-chloro-benzofuran-2-ylmethyl)-4-methyl-piperazin-1-yl]-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone, E123 (95 mg) by a procedure similar to that described for Example 85.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-99f74d88dd1149a496dd8b61753c06d5
来源数据集: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07897618B2
来源说明: uspto-grants-2011_03

反应 SMILES

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][CH:11]3[CH2:16][N:15](C)[CH2:14][CH2:13][N:12]3[C:18]([C:20]3[N:21]=[C:22]([CH3:32])[S:23][C:24]=3[C:25]3[CH:30]=[CH:29][C:28]([F:31])=[CH:27][CH:26]=3)=[O:19])=[CH:7][C:6]=2[CH:33]=1.C1C=C2C(N/N=C3/C4C=CC(S([O-])(=O)=O)=CC=4C=C(S([O-])(=O)=O)C/3=O)=CC=C(S([O-])(=O)=O)C2=CC=1.[Na+].[Na+].[Na+]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][CH:11]3[CH2:16][NH:15][CH2:14][CH2:13][N:12]3[C:18]([C:20]3[N:21]=[C:22]([CH3:32])[S:23][C:24]=3[C:25]3[CH:30]=[CH:29][C:28]([F:31])=[CH:27][CH:26]=3)=[O:19])=[CH:7][C:6]=2[CH:33]=1