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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 598619Generated: October 30, 2026

8-Quinolinecarboxylic acid → (RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-quinolin-8-yl-methanone

https://huagongshe.com/reaction/598619

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Quinolinecarboxylic acidHCID 66582—
ReactantHCID 23146368HCID 23146368—
Product(RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-quinolin-8-yl-methanoneHCID 231463781.8%

Reaction Steps

The title compound (4 mg) was prepared from 2-benzo[b]thiophen-2-ylmethyl-piperidine D83 (133 mg) and 8-quinoline carboxylic acid (109 mg) according to a procedure similar to that described for Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897618B2
Source datasetuspto-grants-2011_03
ORD IDord-acb3219278bc40ca8d4553745bfc89e1
Source noteuspto-grants-2011_03