HCID 59379802, compound → HCID 59379814, compound

HRID 598748Notes

Reaction equation

HRID 598748 reaction equation
[CH3:1][O:2][C:3](=[O:25])[C:4]([C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([O:16][CH2:17][CH2:18][N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)=[CH:8][CH:7]=1)=[O:5]>CO.[Pd]>[CH3:1][O:2][C:3](=[O:25])[CH:4]([OH:5])[C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([O:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)=[CH:8][CH:7]=1

Participants

4

Reactant 1

HCID 59379802HCID 59379802, compound

Product 1

HCID 59379814HCID 59379814, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 23938PalladiumSolvent

Procedure

To a solution of 12 (1 g, 2.9 mmol) in MeOH (10 mL), Pd/C (10 wt %) was added and the mixture stirred at rt under H2 atmosphere. Upon completion of the reaction (monitored by LCMS), the mixture was filtered through celite and the filtrate evaporated to give a yellow oil which solidified upon standing. Calculated mass=345. Observed mass=345.

Workup

  1. customUpon completion of the reaction (monitored by LCMS)
  2. filtrationthe mixture was filtered through celite
  3. customthe filtrate evaporated
  4. customto give a yellow oil which

Sources & evidence

ORD record
ord-4a4637a108dd4243855c9e7ec6d2251d
Source dataset
uspto-grants-2011_03
Patent number
US07897599B2

Reaction notes

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