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HRID599167

反应详情

EQUATION

反应方程式

HRID 599167 的结构方程式

REACTANTS

反应物

2
结构：Cc1nc(N=CN(C)C)sc1C(=O)C=CN(C)C
HCID67218485

未命名化合物

结构：CS(=O)(=O)c1ccc(NC(=N)N)cc1.O=[N+]([O-])O
HCID178504802

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(N)sc1-c1ccnc(Nc2ccc(S(C)(=O)=O)cc2)n1
HCID10044127

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

By condensation of N′-[5-(3-dimethylamino-acryloyl)-4-methyl-thiazol-2-yl]-N,N-dimethyl-formamidine and N-(4-methanesulfonyl-phenyl)-guanidine nitrate. Yellow solid. Anal. RP-HPLC: tR=13.2 min (0-60% MeCN, purity >97%). 1H-NMR (DMSO-d6) δ: 1.98 (s, 3H, CH3), 2.54 (s, 3H, CH3), 7.06 (d, 1H, J=5.5 Hz, pyrimidinyl-H), 7.80 (m, 2H, Ph-H), 8.00 (m, 2H, Ph-H), 8.45 (d, 1H, J=5.5 Hz, pyrimidinyl-H), 10.05 (sbr, 2H, NH2). MS (ESI+) m/z 362.38 [M+H]+ (C15H15N5O2S2 requires 361.44).