Ammonia → HCID 67152226, compound

Participants

Reaction Steps

Prepared from (4s)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and 5-(2-nitrophenyl)-2-furoic acid (Aldrich) according to methods A and C; yield 86 mg, 0.21 mmol (59%): 1H NMR (300 MHz, methanol-d4) δ 2.01 (d, J=13 Hz, 2H), 2.19-2.37 (m, 3H), 2.43 (s, 2H), 3.58 (s, 2H), 3.67 (s, 4H), 4.42 (s, 1H), 6.97 (d, J=4 Hz, 1H), 7.28 (d, J=3 Hz, 1H), 7.62 (dt, J=8, 1 Hz, 1H), 7.73 (dt, J=8, 1 Hz, 1H), 7.82 (dd, J=8, 1 Hz, 1H), 7.93 (dd, J=8, 1 Hz, 1H); MS (DCI/NH3) m/z 368 (M+H)+; Anal. C20H21N3O4.HCl.0.2H2O: C, H, N.

Provenance & Evidence