Ammonia → HCID 67152161, compound

Participants

Reaction Steps

Prepared from (4r)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and 3,4-dichlorobenzoic acid (Aldrich) according to methods A and C; yield 39 mg, 0.10 mmol (49%): 1H NMR (300 MHz, methanol-d4) δ 2.06-2.27 (m, 6H), 2.46 (s, 2H), 3.48 (d, J=12 Hz, 2H), 3.55 (s, 2H), 3.81 (d, J=13 Hz, 2H), 4.25 (s, 1H), 7.65 (d, J=8 Hz, 1H), 7.80 (dd, 1H), 8.07 (d, J=2 Hz, 1H); MS (DCI/NH3) m/z 325 (M+H)+; Anal. C16H18Cl2N2O.HCl. 0.4HCl.0.15C4H8O2: C, H, N.

Provenance & Evidence