HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-[(4s)-1-Azatricyclo[3.3.1.13,7]dec-4-yl]-3-methoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Methoxybenzoic Acid | HCID 11461 | — |
| Reactant | 1-Azatricyclo[3.3.1.1,3,7]decan-4-amine | HCID 15686618 | — |
| Product | N-[(4s)-1-Azatricyclo[3.3.1.13,7]dec-4-yl]-3-methoxybenzamide | HCID 16068050 | — |
Reaction Steps
Prepared from (4s)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine and 3-methoxybenzoic acid (Aldrich) according to method B; 1H NMR (500 MHz, methanol-d4) δ 2.30 (d, J=14 Hz, 6H), 2.40 (s, 2H), 3.49 (s, 2H), 3.60 (s, 3H), 3.79-3.89 (m, 4H), 4.38 (s, 1H), 7.13 (d, J=3 Hz, 1H), 7.33-7.44 (m, 3H); MS (APCI/NH3) m/z 287 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897766B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-769afbe1c3a143f2b991fa0d71bda7e7 |
| Source note | uspto-grants-2011_03 |