Ammonia → N-[(4s)-1-Azatricyclo[3.3.1.13,7]dec-4-yl]-3-trifluoromethoxybenzamide

참여 물질

역할	이름	HCID	투입량
반응물	Ammonia	HCID 222	—
반응물	3-(Trifluoromethoxy)benzoic acid	HCID 66096	—
반응물	1-Azatricyclo[3.3.1.1,3,7]decan-4-amine	HCID 15686618	—
생성물	N-[(4s)-1-Azatricyclo[3.3.1.13,7]dec-4-yl]-3-trifluoromethoxybenzamide	HCID 16068052	—

반응 단계

Prepared from (4s)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine and 3-trifluoromethoxybenzoic acid (Aldrich) according to method B; 1H NMR (500 MHz, methanol-d4) δ 1.96 (d, J=13 Hz, 2H), 2.12 (s, 1H), 2.31 (d, J=13 Hz, 2H), 2.40 (s, 2H), 3.50 (s, 2H), 3.60 (s, 4H), 4.40 (s, 1H), 7.45-7.51 (m, 1H), 7.56-7.62 (m, 1H), 7.74 (s, 1H), 7.82-7.87 (m, 1H); MS (APCI/NH3) m/z 341 (M+H)+.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07897766B2
출처 데이터셋	uspto-grants-2011_03
ORD ID	ord-ec1c1778b5ea4b8e85ee7fc76e4e44b5
출처 메모	uspto-grants-2011_03