Ammonia → HCID 67152200, compound

Participants

Reaction Steps

Prepared from (4r)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and isoquinoline-3-carboxylic acid according to methods A and C. 1H NMR (300 MHz, methanol-d4) δ ppm 2.08-2.34 (m, 5H), 2.51 (s, 2H), 3.42-3.64 (m, 4H), 3.88 (d, J=12.5 Hz, 2H), 4.33 (s, 1H), 7.43 (d, J=8.8 Hz, 2H), 7.68 (d, J=8.8 Hz, 2H), 7.93 (d, J=1.4 Hz, 1H), 8.24 (d, J=1.7 Hz, 1H). MS (DCI/NH3) m/z 308. Anal. Calculated for C19H21N3O.HCl: C, 66.37; H, 6.45; N, 12.22. Found: C, 47.6; H, 5.89; N, 8.71.

Provenance & Evidence