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HRID599251

反应详情

EQUATION

反应方程式

HRID 599251 的结构方程式

REACTANTS

反应物

3
结构：N
HCID222

Ammonia gas

H3N

结构：Cc1nc(-c2ccc(C(=O)O)s2)cs1
HCID614467

5-(2-Methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid

C9H7NO2S2

结构：Cl.NC1C2CC3CC1CN(C3)C2
HCID67152122

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(-c2ccc(C(=O)NC3C4CC5CC3CN(C5)C4)s2)cs1.Cl
HCID67152163

未命名化合物

PROCEDURE

实验过程

Prepared from (4r)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and 5-(2-methylthiazol-4-yl)thiophene-2-carboxylic acid according to methods A and C. 1H NMR (300 MHz, methanol-d4) δ ppm 2.08-2.34 (m, 5H), 2.51 (s, 2H), 2.74 (s, 3H), 3.42-3.64 (m, 4H), 3.88 (d, J=12.5 Hz, 2H), 4.33 (s, 1H), 7.49 (d, J=4.1 Hz, 1H), 7.68 (s, 1H), 7.79 (d, J=4.1 Hz, 1H). MS (DCI/NH3) m/z 360.