HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 1H-Indazole-4-carboxylic acid(4r)-(1-azatricyclo[3.3.1.13,7]dec-4-yl)-amide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 1H-indazole-4-carboxylic acid | HCID 21982323 | — |
| Reactant | 1-Azatricyclo[3.3.1.1,3,7]decan-4-amine hydrochloride | HCID 67152122 | — |
| Product | 1H-Indazole-4-carboxylic acid(4r)-(1-azatricyclo[3.3.1.13,7]dec-4-yl)-amide hydrochloride | HCID 67152130 | — |
Reaction Steps
Prepared from (4r)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and 1H-indazole-4-carboxylic acid according to methods A and C. 1H NMR (300 MHz, methanol-d4) δ ppm 2.08-2.34 (m, 5H), 2.51 (s, 2H), 3.42-3.64 (m, 4H), 3.88 (d, J=12.5 Hz, 2H), 4.33 (s, 1H), 7.42-7.52 (m, 1H), 7.58-7.64 (m, 1H), 7.72 (d, J=8.5 Hz, 1H), 8.33 (s, 1H). MS (DCI/NH3) m/z 297.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897766B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-1ce97d17ca714f24bd9e54d5d5fe0f87 |
| Source note | uspto-grants-2011_03 |