m-Chloroperbenzoic acid → HCID 67053947, compound

Participants

Reaction Steps

m-Chloroperoxybenzoic acid (65%, 210 mg, 0.72 mmol) was added to a solution of N-(3,5-dimethylphenyl)-2-(quinolin-4-ylmethylthio)pyridine-3-carboxamide (Compound No. 1-3,200 mg, 0.50 mmol) in anhydrous dichloromethane (5.0 mL) under ice-cooling, and then the mixture was stirred at room temperature for 3 hours. The precipitated solid was filtered off with chloroform (30 mL) and 1N sodium hydroxide aqueous solution (30 mL), and washed. The resulting solid was dried at 50° C. under reduced pressure to give 150 mg of the target compound as a white solid (Yield: 70%).

Provenance & Evidence