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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 599496Generated: October 27, 2026

Hydrogen iodide → 2-[(6-Chloropyridin-3-yl)methyl]tetrahydro-1H-1lambda4-thiophen-1-imine-1-oxide

https://huagongshe.com/reaction/599496

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen iodideHCID 24841—
ReactantSodium AzideHCID 33557—
Reactant2-Chloro-5-[(1-oxidotetrahydrothien-2-yl)methyl]-pyridineHCID 59215222—
Product2-[(6-Chloropyridin-3-yl)methyl]tetrahydro-1H-1lambda4-thiophen-1-imine-1-oxideHCID 59215224—

Reaction Steps

2-[(6-Chloropyridin-3-yl)methyl]tetrahydro-1H-1λ4-thiophen-1-imine-1-oxide was prepared from 2-chloro-5-[(1-oxidotetrahydrothien-2-yl)methyl]-pyridine by the method as described in Example I-H using NaN3 as the iminating agent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897782B2
Source datasetuspto-grants-2011_03
ORD IDord-70e4c1d16832483fb96b58b8b2e4b6e2
Source noteuspto-grants-2011_03