Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 599613Generated: October 29, 2026

tert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate → 5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochloride

https://huagongshe.com/reaction/599613

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylateHCID 67067169—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
Product5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochlorideHCID 67067176216.8%

Reaction Steps

tert-Butyl N′-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate (90 mg) was dissolved in a solution of 4 N hydrogen chloride in dioxane (1 mL), and the reaction solution was stirred at room temperature for 70 minutes. The reaction solution was concentrated under reduced pressure to obtain 81 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897632B2
Source datasetuspto-grants-2011_03
ORD IDord-561eb847ae33430bbd5983e742b2aac0
Source noteuspto-grants-2011_03