HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate → 5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate | HCID 67067169 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochloride | HCID 67067176 | 216.8% |
Reaction Steps
tert-Butyl N′-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate (90 mg) was dissolved in a solution of 4 N hydrogen chloride in dioxane (1 mL), and the reaction solution was stirred at room temperature for 70 minutes. The reaction solution was concentrated under reduced pressure to obtain 81 mg of the title compound. The property value of the compound is as follows.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897632B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-561eb847ae33430bbd5983e742b2aac0 |
| Source note | uspto-grants-2011_03 |