Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 599684Generated: October 30, 2026

1,2-Dichloroethane → HCID 11202435, compound

https://huagongshe.com/reaction/599684

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethylamine, hydrochlorideHCID 10473—
ReactantHCID 11224774HCID 11224774—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
ProductHCID 11202435HCID 1120243576%

Reaction Steps

2-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzo[b]thiophene-6-carboxylic acid (175 mg, 0.387 mmol), DMAP (142 mg, 1.16 mmol), EDC (111 mg, 0.580 mmol), and dimethylamine hydrochloride (47 mg, 0.580 mmol) are reacted analogous to Example 3 to afford the title compound (140 mg, 76%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897789B2
Source datasetuspto-grants-2011_03
ORD IDord-7cf282140610420485bd0be885a4ffb0
Source noteuspto-grants-2011_03