HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57835396, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Bromopinacolone | HCID 21642 | — |
| Reactant | HCID 57835403 | HCID 57835403 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 57835396 | HCID 57835396 | 95% |
Reaction Steps
5-[1-Ethyl-1-(4-hydroxy-3-methyl-phenyl)-propyl]-benzo[b]thiophene-2-carboxylic acid ethyl ester (5.97 g, 15.6 mmol), 1-bromopinacolone (4.20 g, 23.4 mmol), and K2CO3 (6.46 g, 46.8 mmol) in acetone (100 mL) are reacted analogous to Example 1D to provide the title compound (7.10 g, 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897789B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-ffb0244eb68f47e3ab5b736df45f949c |
| Source note | uspto-grants-2011_03 |