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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 599736Generated: October 30, 2026

HCID 66941684, compound → HCID 57807669, compound

https://huagongshe.com/reaction/599736

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66941684HCID 66941684—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 57807669HCID 57807669—

Reaction Steps

A suspension of 5.13 g (14.3 mmol) ethyl 3-[4-(1-benzyl-piperidin-4-yl)-piperazin-1-yl]-propionate and 1.0 g 10% Pd/C in 100 mL EtOH was hydrogenated for 2 h at 50° C. and 50 psi hydrogen pressure. The catalyst was filtered off and the filtrate was evaporated to dryness. The oily product was reacted further without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897603B2
Source datasetuspto-grants-2011_03
ORD IDord-0b2317ba9a3b4dcb88bec28b1359196d
Source noteuspto-grants-2011_03