HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66941684, compound → HCID 57807669, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66941684 | HCID 66941684 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57807669 | HCID 57807669 | — |
Reaction Steps
A suspension of 5.13 g (14.3 mmol) ethyl 3-[4-(1-benzyl-piperidin-4-yl)-piperazin-1-yl]-propionate and 1.0 g 10% Pd/C in 100 mL EtOH was hydrogenated for 2 h at 50° C. and 50 psi hydrogen pressure. The catalyst was filtered off and the filtrate was evaporated to dryness. The oily product was reacted further without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897603B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-0b2317ba9a3b4dcb88bec28b1359196d |
| Source note | uspto-grants-2011_03 |