HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-5-(1-Amino-2-(dimethylamino)ethyl)-2-chlorobenzonitrile → HCID 76072990, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-5-(1-Amino-2-(dimethylamino)ethyl)-2-chlorobenzonitrile | HCID 90190353 | — |
| Reactant | 4-oxo-1H-1,2,3-benzotriazine-8-carboxamide | HCID 178513613 | — |
| Product | HCID 76072990 | HCID 76072990 | — |
Reaction Steps
Compound 17 was prepared following general synthetic scheme 7 wherein (S)-5-(1-amino-2-(dimethylamino)ethyl)-2-chlorobenzonitrile was reacted with 4-hydroxybenzo[d][1,2,3]-triazine-8-carboxamide to give the title compound. LC-MS [397 (M+1)], 1H NMR (400 MHz, DMSO-d6): δ 9.31 (s, 1H), 8.81 (d, 1H), 8.63 (d, 1H), 8.55 (d, 1H), 8.15 (d, 1H), 8.05-8.01 (m, 2H), 7.88 (dd, 1H), 7.72 (d, 1H), 5.78 (q, 1H), 2.95-2.89 (m, 1H), 2.62-2.58 (m, 1H), 2.24 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440968B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-4e40ee5ece9747d0b094d1eca0bd41c5 |
| Source note | uspto-grants-2016_09 |