2,4-Dihydroxybenzaldehyde → HCID 86637669, compound

Participants

Reaction Steps

(3-Acetylaminophenylsulfamoyl)acetic acid ethyl ester (280 mg, 0.93 mmol), 2,4-dihydroxybenzaldehyde (516 mg) and piperidine (10 mg) were added to 9 mL of ethanol, and the mixture was heated under reflux overnight. It was then purified by silica gel chromatography (methylene chloride:methanol=30:1) to yield the title compound (304 mg, 87%).

Provenance & Evidence