HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Chloro-beta-nitrostyrene → HCID 59752519, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Chloro-beta-nitrostyrene | HCID 95339 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Solvent | 4-Chlorobenzylamine | HCID 66036 | — |
| Product | HCID 59752519 | HCID 59752519 | 52.4% |
Reaction Steps
The title compound (260.2 mg) was prepared from 0.55 g of 4-oxo-piperidine-1-carboxylic acid tert-butyl ester, 340 μL of 4-chlorobenzylamine, and 0.51 g of (2-nitro-vinyl)-4-chlorobenzene. MS (ESI): exact mass calculated for C20H18Cl2N2, 356.08. found, m/z 357.1 [M+H]+. 1H NMR (500 MHz, CD3OD): 7.37-7.31 (m, 6H), 7.17-7.13 (m, 3H), 5.15 (s, 2H), 4.35 (s, 2H), 3.51 (t, J=6.3 Hz, 2H), 2.85 (t, J=6.3 Hz, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897771B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-39656a313be34609b4a5b0bc2d4b03b2 |
| Source note | uspto-grants-2011_03 |