Diethyl Ether → HCID 42641556, compound

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Reaction Steps

A solution of (S)-tert-butyl 2-((S)-2-(4-(3-(2-(tert-butyldimethylsilyloxy)ethyl)-2-oxo-2,3-dihydrobenzo[d]thiazol-6-yl)phenyl)-1-cyanoethylcarbamoyl)piperidine-1-carboxylate (103 mg) in formic acid (1 ml) was stirred at 50° C. for 10 min. The solvent was removed in vacuo and the residue was purified by flash silica chromatography eluting with 1:14 2M ammonia in methanol/DCM to give, after trituration with diethyl ether, the title compound (60 mg) as a white solid.

Provenance & Evidence