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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 600705Generated: October 25, 2026

1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-4,5-dihydro-, ethyl ester → 3-Bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid

https://huagongshe.com/reaction/600705

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Pyrazole-5-carboxylic acid, 3-bromo-1-(3-chloro-2-pyridinyl)-4,5-dihydro-, ethyl esterHCID 10065383—
ReactantHCID 67271481HCID 67271481—
Product3-Bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acidHCID 11587535—

Reaction Steps

The following Example 10 illustrates an alternative preparation of ethyl 3-bromo-1-(3-chloro-2-pyridinyl)-4,5-dihydro-1H-pyrazole-5-carboxylate, which can be used to prepare, for example, ethyl 3-bromo-1-(3-chloro-2H-pyridinyl)-1H-pyrazole-5-carboxylate (i.e. product of Example 9, Step B).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902231B2
Source datasetuspto-grants-2011_03
ORD IDord-26b6907bf81544329849c9b3c2083f08
Source noteuspto-grants-2011_03