N-Hydroxy-3-pyridinecarboximidoyl chloride → 7-[cis-3-(3-Pyridyl)-3a,4,6,6a-tetrahydropyrrolo[3,4-d]isoxazol-5-yl]-1-cyclopropyl-8-methoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Participants

Role	Name	HCID	Charge
Reactant	N-Hydroxy-3-pyridinecarboximidoyl chloride	HCID 53404818	—
Reactant	7-[cis-3-(2-Pyridyl)-3a,4,6,6a-tetrahydropyrrolo[3,4-d]isoxazol-5-yl]-1-cyclopropyl-8-methoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid	HCID 68974402	—
Product	7-[cis-3-(3-Pyridyl)-3a,4,6,6a-tetrahydropyrrolo[3,4-d]isoxazol-5-yl]-1-cyclopropyl-8-methoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid	HCID 68972561	—

The title compound was prepared in an analogous manner to acid 122, but using chloro oxime 2f. Acid 123 was isolated.