Hydrazine hydrate (1:1) → HCID 57555561, compound

Participants

Reaction Steps

Phthalimide 108 (241 mg; 0.409 mmol) and hydrazine hydrate (0.03 mL) in ethanol (5 mL) were heated at reflux temperature under a nitrogen atmosphere for 23 hours. After cooling, the thick reaction mixture suspension was filtered. The solid was washed with methylene chloride, water and dried to yield amine 200 as an off-white solid.

Provenance & Evidence