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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 600794Generated: October 30, 2026

8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-one → HCID 11964285, compound

https://huagongshe.com/reaction/600794

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-oneHCID 11955840—
ReactantHCID 11964239HCID 11964239—
ProductHCID 11964285HCID 11964285—

Reaction Steps

The title compound was prepared using the procedure as described in Example 2, substituting the product of Example 15C for the product of Example 1I. 1H NMR (DMSO-d6) δ 9.08 (s, 1H), 7.58 (d, 1H, J=7.3 Hz), 7.26-7.39 (m, 4H), 7.04-7.12 (m, 2H), 6.83 (d, 1H, J=7.2 Hz), 4.81 (d, 1H, J=4.1 Hz), 3.93 (m, 1H), 2.73-2.97 (m, 4H), 2.33 (s, 3H), 1.86 (m, 1H), 1.61 (m, 1H); MS (ESI+) m/z 321 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902236B2
Source datasetuspto-grants-2011_03
ORD IDord-860bcd55d4db43b09d30d0b1e248d7d3
Source noteuspto-grants-2011_03