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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 600800Generated: October 29, 2026

8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-one → HCID 11964317, compound

https://huagongshe.com/reaction/600800

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-oneHCID 11955840—
ReactantHCID 11964315HCID 11964315—
ProductHCID 11964317HCID 11964317—

Reaction Steps

The title compound was prepared using the procedure as described in Example 2, substituting the product of Example 17C for the product of Example 1I. 1H NMR (DMSO-d6) δ 8.66 (s, 1H), 7.53 (d, J=7.8 Hz, 1H), 7.01 (t, J=7.8 Hz, 1H), 6.75 (d, J=7.5 Hz, 1H), 6.44 (s, 1H), 4.76 (d, J=3.7 Hz, 1H), 3.94 (m, 1H), 2.61-2.99 (m, 4H), 1.84 (m, 1H), 1.60 (m, 1H), 1.22 (s, 9H); MS (ESI+) m/z 287 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902236B2
Source datasetuspto-grants-2011_03
ORD IDord-80c85f27f4cf4bc3b3c9744ab4714dfd
Source noteuspto-grants-2011_03